Left Ventricular Geometrical and Functional Changes in Patients with ESRD on Hemodialysis Programme

Abstract

(ESRD) is considered that increase cardiac morbidity, which be a primary factor of increased mortality for patients with ESRD; cardiovascular complications of ESRD account for approximately 40% of deaths in these patients. The aim of this study is to assess the structural and functional changes of the left ventricle in patients with End Stage Renal Disease (ESRD) on haemodialysis. Chronic kidney disease (CKD) patients on hemodialysis experience higher rates of cardiac morbidity and mortality, with almost 40% of deaths resulting from cardiovascular complications. This study compared 50 CKD patients on hemodialysis with 50 healthy subjects from hospitals in Baghdad, Iraq, from 15th March 2021 to 18th May 2022. Echocardiography was used to evaluate left ventricular mass index, volume, and ejection fraction. Additionally, clinical and biochemical assessments were conducted for all participants. The patients were categorised into four groups according to echocardiographic abnormalities: left ventricular hypertrophy (58%), left ventricular dilatation (20%), systolic dysfunction (20%), and normal echocardiogram (22%). Left ventricular disorders were significantly linked with hypertension, high serum creatinine, low haemoglobin, and long-term renal failure. Most of the patients with ESRD had abnormal echocardiographic abnormalities, and most findings were LVH, aggressive control of blood pressure, and anemia. Creatinine can help to prevent these abnormalities

Keywords

Haemoglobin, Hemodialysis, hypertrophy, and echocardiogram