Abstract

Background: Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous apparatus. Vitamin D controls the immune system and the proliferation and differentiation of sebocytes and keratinocytes. In addition, it has antioxidant and anti‑comedogenic properties. Serum Vitamin D levels were previously estimated in AV patients with conflicting results. Objective: The aim of this study is to evaluate the serum Vitamin D levels among Iraqi patients with acne vulgaris and to assess the association between vitamin D and disease severity. Method and material: This cross_sectional study was carried out in the Department of Dermatology and Venereology at Al-Yarmuk teaching hospital during period of October 2021 to March 2022.Vitamin D levels were estimated in 69 iraqi acne patients using the enzyme‑linked immunosorbemt assay technique. Results: There was a statistically significant low vitamin D levels in Iraqi’s acne patients (P – value = 0.000). Vitamin D levels were lower in moderate and severe cases than mild cases. Conclusions: Vitamin D may have a role in the pathogenesis of acne vulgaris. Further studies on a larger number of patients are recommended to confirm the validity of our results and to provide a clearer understanding of the correlation between vitamin D and acne severity

Keywords

Vitamin D3, Acne Severity, Iraqi Patients