Abstract

Benign prostatic hyperplasia (BPH) is a histological diagnosis associated with disordered growth of connective tissue, smooth muscle, and glandular epithelium. BPH can compress the urethra and cause bladder outlet obstruction (BOO). BOO can manifest itself in the form of lower urinary tract symptoms (LUTS), infections, retention, and other adverse events. BPH and BOO have a significant impact on the health and health costs of older men. As the world’s population ages, the incidence and prevalence of BPH and LUTS are increasing rapidly. Immutable risk factors such as age, genetics, and geography  play important roles in the pathogenesis of BPH and BOO, but recent data are new  for treatment and prevention, such as sex steroid hormones and metabolic syndrome. Revealed variable risk factors that provide a path Syndrome, and cardiovascular disease-disease, obesity, diabetes, diet, physical activity and inflammation. Epidemiological studies identify the natural history, definitions, and key risk factors for BPH and BOO

Keywords

Etiology, benign prostatic hyperplasia, bladder outflow obstruction, epidemiology, genetics, public health