Sarcouncil Journal of Medicine and Surgery

Abstract: Background: Comparative study of efficacy of topically applied luliconazole cream against topically applied ketoconazole cream in pitryiasis versicolor treatment. Method : a research on 48 participants diagnosed by clinical examination and mycological test using KOH to verify the presence of Malassezia in pitryiasis versicolor and the follow-up of the patients after 2 weeks and 4 weeks of the topical therapy of luliconazole cream and ketoconazole cream. Result: there are 48 participants enrolled in the current study, with a mean age of 29±3.38, a predominance of male patients (73%), and a mean duration of symptoms of 32.2±2.244. Luliconazole cream shows higher efficacy against pityriasis versicolor after 2 weeks of application (53.85%), while ketoconazole cream shows lower efficacy (40.91%). After 4 weeks of topical application, luliconazole shows higher efficacy (88.46%) than ketoconazole (81.82%). Conclusion: The present study clarify that topical luliconazole exhibits a greater efficacy than ketoconazole in treatment of pitryiasis versicolor.