Sarcouncil Journal of Medical Sciences

Abstract: Background: Liver disease is a significant health problem worldwide, particularly in developing countries like Iraq, where it is associated with high levels of morbidity and mortality where The aim of this research is to evaluate the impact of liver disease on the quality of life (QoL) of patients in various medical centers across Iraq so according to method A cross-sectional, from different hospitals from Iraq study was carried out between March 8, 2024, and June 6, 2025. Seventy liver disease patients were enrolled from outpatient and inpatient departments. QoL was evaluated by validated tools, which include the Short Form Health Survey (SF-36), the Hospital Anxiety and Depression Scale (HADS), and the Chronic Liver Disease Questionnaire (CLDQ). Demographic and clinical characteristics were also gathered. The finding was found identified that those in late stages of liver disease had significantly lower QoL scores in both physical and mental health domains than those in the early stages. Furthermore, specifically, anxiety and depression were greater in those with more advanced disease. Correlation studies demonstrated strong negative correlations between disease severity and QoL measures. The findings indicate the significant burden of liver disease on QoL, with a call for holistic care models that target both physical and psychological components of patient health, where the study provides important insight into the experiences of liver disease patients in Iraq, with a case for better healthcare facilities.