Sarcouncil Journal of Medical Sciences

Abstract: To examine the range of maternal complications and neonatal morbidity in a modern cohort based on the severity of preeclampsia, with the risk gradients and prognostic variables measured by intensive prospective follow-up as well as 320 singleton pregnancies were followed up and prospectively recruited at the main obstetric centre in Minsk between January 2022 and December 2023 and segments into normotensive (n=110), mild preeclamptic (n=105), or severe preeclamptic (n=105) groups including 320 singleton pregnancies above 20 week and siagnostic threshold was based on revised ACOG parameters, which focused on end-organ parameters where A combination of analytic strategy comprised both contingency tables, parametric group comparison and multivariate modelling, which reached a statistical power of 85 percent to identify 25 percent intergroup difference. Incidence of maternal complications increased geometrically: 8%, 24%, and 52%; severe cases had 14-fold increased risk of seizures, 22-fold increased hepatic dysfunction, 31% increased transfusion, 92% increased surgical delivery, and 38% increased organ support (omnibus p<0.001; adjusted odds of severe to control 13.8, CI 5.7-33.4). Foetal compromise burden equal: 15, 43, 69, composites, expressed 82, very preterm rates, 61, growth discordance, 198/1000 mortality index, 71, tertiary neonatal dependency. The regression analysis has established adiposity (OR 2.9), microcytosis (OR 3.5), and placental-phase onset (OR 4.3) as the major determinants of severity. Conclusion: Preeclampsia poses exponential risks based on the intensity of diagnosis, which bears 10-14-fold adversity changeable to specific screening, hematinic repletion, and emerging neuroprotection. This requires further development of the algorithms of antenatal surveillance as a means of countering cascading organ failure within resource-constrained obstetric ecologies.