Sarcouncil Journal of Medical Sciences

Abstract: Background: Urinary tract infections (UTIs) are common bacterial infections worldwide, mainly due to Escherichia coli (E. coli). UTIs present important consequences for both patient health and healthcare systems, mainly through recurrent infection and antibiotic resistance. Objective: This research purports to examine the effect of E. coli infections in 92 UTI patients during a 12-month follow-up period on treatment outcome, recurrence, and antibiotic resistance patterns. Methods: 92 UTI patients were prospectively enrolled. Demographic data, clinical symptoms, laboratory results, and treatment responses at 1, 3, 6, and 12 months were collected. Urine cultures identified E. coli, and antibiotic susceptibility was established. Recurrence and treatment satisfaction were noted via follow-up questionnaires. Results: Among the participants, the study revealed that 21.7% of the patients experienced recurrence within a year. There was resistance to the common UTI drugs, which was also observed to have a great bearing on medication regimen adherence. The health-related quality of life scores among the patients revealed moderate dysfunction, demonstrating a negative effect on daily activities. Conclusion: E. coli continues to be a formidable pathogen in the world of UTIs with profound implications amidst emerging antibiotic resistance. Greater consideration of the interplay between demographic variables and treatment response could form the basis of improved management protocols, decrease recurrence, and enhance patient quality of life overall.