Sarcouncil Journal of Plant and Agronomy

Abstract: Instant eating patterns such as fast food have become a habit in society. Fast food has a high fat content and minimal fiber, so it is often associated with an increase in total cholesterol levels in the blood plasma. Ginseng leaves (Talinum Paniculatum) have anticholesterol properties due to the chemical compounds such as flavonoids, saponins, and tannins. Flavonoid compounds are able to release cholesterol found in the walls of blood vessels. The purpose of this study was to determine whether there was anticholesterol activity and EC50 value in the ethanol extract of ginseng leaves with a concentration range of 1500; 2500; 3500; 4500; and 5500 ppm. The samples extracted by maceration method with 96% ethanol obtained % an extract yield of 12.22%. The ethanol extract of ginseng leaves was tested for anticholesterol activity using the Lieberman-Burchard method and then measured using UV-Vis spectrophotometry at a wavelength of 669 nm for 5 minutes. The results reported that the ethanol extract of ginseng leaves possessed an anticholesterol activity with an EC50 value of 4040.7 ppm