Which Is the Predominant Pattern of Mineral & Bone Disease (High vs Low Turnover) Among Dialysis Patients in Baghdad Teaching Hospital

Abstract

Background: A common complication of CKD is a metabolic bone disease. It is one of a wide range of mineral metabolism disorders that can occur in clinical sitting and have both skeletal and non-skeletal implications. Abnormalities found in laboratory examinations, parathyroid gland dysfunction, abnormality in bone metabolism, and abnormality in soft tissue calcification are the three components of CKD-MBD. Objective: The study’s goal is to find out which are the most common. Common type of CKD-MBD among dialysis patients in Baghdad Teaching Hospital based on laboratory parameters. Materials and methods: The study included 100 ESRD patients who underwent HD treatment at an outpatient dialysis center (Baghdad Teaching Hospital) if they have three months or more of dialysis vintage. Level of PTH, ALP, calcium, and phosphorus Normal laboratory procedures were used to assess the results. Results: 80% of the sample had CKD-MBD, and the high turnover bone disease was 38%, while the low turnover bone disease was 19%. There was no significant association between MBD and pattern and each of age or gender. No significant association was found between MBD pattern and each of the causes of CKD, type of access, and associated disease. Conclusion: MBD are very prevalent in our patients (80%), and the most common pattern of MBD is a high turnover bone disease